… • Two or more relatives with early onset prostate cancer, ie … G84E and association to
significant prostate cancer is … pathology after prostatectomy is not known. We aim to evaluate if …

… early-onset prostate cancer and/or a positive family history of … Its association with age at
onset and advanced disease in … of relevant clinical data but also histopathologic confirmation of …

… to early onset and aggressive disease [26,27], PCa, like most … (SNP) with positive or negative
associations are becoming … and aggressive PCa pathology compared to Caucasian and …

… Data from another study indicate a positive association between birthweight and colon cancer
risk in adulthood 30 . Exposure to ionizing radiation and age at menarche are other factors …

… -wide association studies have led to … early onset of the disease and men with inherited
germline variants in DNA repair genes are particularly at risk for harbouring aggressive histology. …

… is intraductal pathology or if the family history is suspicious. … at the European Society for
Medical Oncology 2019 meeting … a higher risk of PCa and early-onset disease, as supported by …

… advanced, early-onset, and familial prostate cancer genetic … of 441 patients with known
pathology), respectively. Although the … Medical Research Council and the Cancer Association of …

… While early onset, multiple tumors, and family cancer history … population and occur in those
with a positive family history. … In a study of 2160 patients, no significant associations were …

… the association of a GPV with the biology of a given cancer, … of histological diagnosis of
several family members with, … have a positive family history of any cancer and family history of …

… cancers with one of them being diagnosed at age <50, and patients with a strong family history
be … For example, we observed significantly more mucinous and signet ring histology in the …